Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949126 | 0.79 | GABRA1 (0.48) | TRPA1PTGS2GABRA1SIGMAR1 | |
| SCHEMBL29527566 | 0.77 | VCP (0.55) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL154905 | 0.77 | VCP (0.55) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL11127611 | 0.72 | VCP (0.50) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL7576321 | 0.72 | IDO1 (0.50) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL2394174 | 0.72 | DPEP1 (0.49) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL1907796 | 0.72 | DPEP1 (0.49) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL30667977 | 0.72 | SMN1; SMN2 (0.46) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL26684281 | 0.72 | SMN1; SMN2 (0.46) | VCPNPC1RAB9ATDP1MAOB | |
| SCHEMBL8539278 | 0.71 | MAPT (0.55) | VCPNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640247-B1 | SYK INHIBITOR AND USE METHOD THEREFOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |