Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193352 | 0.94 | NAMPT (0.32) | RORCNAMPTMMP2MMP9MMP8 | |
| SCHEMBL2195371 | 0.92 | PTGDR2 (0.32) | NAMPTCHRM4 | |
| SCHEMBL2411039 | 0.91 | ABCC9 (0.34) | NAMPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL2194752 | 0.88 | MMP2 (0.33) | NAMPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL2409439 | 0.87 | MMP2 (0.33) | NAMPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL2407582 | 0.86 | MET (0.38) | NAMPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL2413757 | 0.86 | SLC6A9 (0.35) | RORCNAMPTMMP2MMP9MMP8 | |
| SCHEMBL2192366 | 0.86 | DCTPP1 (0.31) | NAMPTMMP2MMP9MMP8MMP13 | |
| SCHEMBL2409148 | 0.86 | BRD4 (0.33) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2194193 | 0.85 | GPBAR1 (0.30) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172275-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172275-A1 | PYRROLE COMPOUNDS | PRLHR, C1R, C1S | RORC 786/4885NAMPT 1814/4885MMP2 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.