Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.59 |
| ▸ | TUBB | P07437 | 2/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938320 | 0.85 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2194473 | 0.83 | PTGDR2 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4322899 | 0.83 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29819713 | 0.83 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1503818 | 0.79 | KMT2A (0.56) | ALOX15ALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL2190526 | 0.77 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8959676 | 0.77 | DRD2 (0.62) | ALDH1A1HPGDCYP1A2CYP2C19DRD2 | |
| SCHEMBL9033950 | 0.77 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24375425 | 0.76 | KMT2A (0.58) | ALOX15ALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL3283431 | 0.76 | ALDH1A1 (0.69) | ALOX15ALDH1A1HPGDCYP1A2XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172244-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-07-14 | — | — | US | disclosed |
| EP-2252586-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009105722-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172244-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR65, GPR39 | TUBB4A 3880/4885TUBB 3718/4885TUBA3C 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.