Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21554146 | 0.90 | CYP4F2 (0.38) | ALOX5MAOBMAOAHTTPOLB | |
| SCHEMBL21994125 | 0.89 | ALOX5 (0.37) | ALOX5MAOBMAOAHTTPOLB | |
| SCHEMBL25660991 | 0.87 | MAOB (0.37) | MAOBMAOAKDM4EGAA | |
| SCHEMBL21993633 | 0.81 | ALOX5 (0.44) | ALOX5MAOBMAOAHTTPOLB | |
| SCHEMBL21998476 | 0.79 | MAOA (0.36) | MAOBMAOAKDM4EGAA | |
| SCHEMBL19640138 | 0.75 | CYP4F2 (0.40) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL19640145 | 0.74 | HTT (0.37) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL27834366 | 0.72 | HTT (0.42) | ALOX5HTTPOLBKDM4ETP53 | |
| SCHEMBL21998475 | 0.71 | PLA2G2A (0.36) | MAOBMAOAHTTPOLB | |
| SCHEMBL26397846 | 0.71 | PPARA (0.38) | HTTPOLBKDM4ETP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | OPRL1, OPRK1, OPRM1 | ALOX5 222/4885MAOB 1484/4885MAOA 776/4885 |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | OPRL1, OPRK1, OPRM1 | ALOX5 222/4885MAOB 1484/4885MAOA 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.