Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998476 | 0.84 | MAOA (0.36) | ALOX15ALDH1A1THRATHRBAKR1B1 | |
| SCHEMBL21998478 | 0.83 | MAOA (0.35) | ALDH1A1AKR1B1MAOAMAOB | |
| SCHEMBL9204687 | 0.80 | THRA (0.42) | PLA2G2AALDH1A1THRATHRBMAOA | |
| SCHEMBL19578871 | 0.77 | PLA2G2A (0.48) | PLA2G2AALDH1A1HPGDRARB | |
| SCHEMBL18946302 | 0.76 | PLA2G2A (0.39) | PLA2G2APOLBALOX15HTTALDH1A1 | |
| SCHEMBL16645345 | 0.75 | PLA2G2A (0.50) | PLA2G2AALDH1A1HPGDTHRATHRB | |
| SCHEMBL16447428 | 0.75 | PLA2G2A (0.40) | PLA2G2APOLBALOX15HTTALDH1A1 | |
| SCHEMBL3607900 | 0.73 | ALOX15 (0.45) | PLA2G2APOLBALOX15HTTALDH1A1 | |
| SCHEMBL4141214 | 0.72 | PLA2G2A (0.59) | PLA2G2AALDH1A1HPGDTHRATHRB | |
| SCHEMBL21994124 | 0.71 | ALOX5 (0.38) | POLBHTTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | OPRL1, OPRK1, OPRM1 | PLA2G2A 1584/4885POLB 3014/4885ALOX15 678/4885 |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | OPRL1, OPRK1, OPRM1 | PLA2G2A 1584/4885POLB 3014/4885ALOX15 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.