Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25660991 | 0.92 | MAOB (0.37) | MAOAMAOBALOX15AKR1B1LDHA | |
| SCHEMBL21994125 | 0.87 | ALOX5 (0.37) | MAOAMAOBKDM4EGAA | |
| SCHEMBL21998475 | 0.84 | PLA2G2A (0.36) | MAOAMAOBALOX15AKR1B1ALDH1A1 | |
| SCHEMBL21998478 | 0.83 | MAOA (0.35) | MAOAMAOBAKR1B1KDM4EALDH1A1 | |
| SCHEMBL21994124 | 0.79 | ALOX5 (0.38) | MAOAMAOBKDM4EGAA | |
| SCHEMBL21554146 | 0.76 | CYP4F2 (0.38) | MAOAMAOBALOX15KDM4EGAA | |
| SCHEMBL26397841 | 0.74 | ALOX15 (0.36) | ALOX15AKR1B1LDHALDHBKDM4E | |
| SCHEMBL21976827 | 0.71 | ALOX15 (0.39) | ALOX15AKR1B1LDHALDHBKDM4E | |
| SCHEMBL21993633 | 0.68 | ALOX5 (0.44) | MAOAMAOBALDH1A1KMT2A | |
| SCHEMBL15413030 | 0.67 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | OPRL1, OPRK1, OPRM1 | MAOA 776/4885MAOB 1484/4885ALOX15 678/4885 |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | OPRL1, OPRK1, OPRM1 | MAOA 776/4885MAOB 1484/4885ALOX15 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.