Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791578 | 0.86 | ADRA2A (0.80) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL15901656 | 0.85 | ALDH1A1 (0.65) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL25167314 | 0.83 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL24011524 | 0.83 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL13367467 | 0.79 | KMT2A (0.54) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL20062968 | 0.78 | KMT2A (0.55) | ADRA2AADRA2BADRA2CKMT2ARAD52 | |
| SCHEMBL25454723 | 0.77 | ADRA2A (0.71) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL3948184 | 0.76 | FADS1 (0.69) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL30743841 | 0.74 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AKMT2A | |
| SCHEMBL8352436 | 0.74 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081800-A1 | ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-11 | — | — | WO | disclosed |
| US-11001778-B2 | Lubricant composition | BASF SE (DE) | 2021-05-11 | — | — | US | disclosed |
| US-20200239803-A1 | Lubricant Composition | BASF SE (DE) | 2020-07-30 | — | — | US | disclosed |
| US-10655079-B2 | Lubricant composition | BASF SE (DE) | 2020-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10655079-B2 | Lubricant composition | SOD1, LPO, GPX4 | ADRA2A 2520/4885ADRA2B 3100/4885ADRA2C 3245/4885 |
| US-20200239803-A1 | Lubricant Composition | SOD1, LPO, GPX4 | ADRA2A 2571/4885ADRA2B 3159/4885ADRA2C 3307/4885 |
| US-11001778-B2 | Lubricant composition | SOD1, LPO, GPX4 | ADRA2A 2571/4885ADRA2B 3159/4885ADRA2C 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.