Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18501122 | 0.98 | MGLL (0.36) | FAAHMGLLKMT2ASMN1; SMN2 | |
| SCHEMBL18392597 | 0.98 | MGLL (0.36) | FAAHMGLLKMT2ASMN1; SMN2 | |
| SCHEMBL23340953 | 0.98 | FAAH (0.35) | FAAHMGLLKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19991910 | 0.97 | MGLL (0.37) | FAAHMGLLKMT2ASMN1; SMN2 | |
| SCHEMBL24049292 | 0.96 | FAAH (0.33) | FAAHMGLLKMT2ASMN1; SMN2 | |
| SCHEMBL23153542 | 0.90 | FAAH (0.31) | FAAHMGLL | |
| SCHEMBL20034776 | 0.84 | FAAH (0.35) | FAAHMGLLKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23690144 | 0.77 | LMNA (0.32) | MAPT | |
| SCHEMBL20931040 | 0.76 | MEN1 (0.31) | FAAHMGLLKMT2A | |
| SCHEMBL22217494 | 0.76 | KMT2A (0.35) | FAAHMGLLKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200158737-A1 | METHODS OF MEASURING UBIQUITIN-LIKE MODIFICATIONS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200158737-A1 | METHODS OF MEASURING UBIQUITIN-LIKE MODIFICATIONS | UCHL1, UCHL3, UCHL5 | FAAH 1480/4885MGLL 1851/4885KMT2A 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.