Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22012760 | 0.86 | HTR2C (0.34) | CACNA1GCACNA1BCACNA1CCA2HTR2C | |
| SCHEMBL25033756 | 0.83 | CACNA1G (0.35) | CACNA1GCACNA1BCACNA1CRIPK1HTR2C | |
| SCHEMBL22012914 | 0.82 | ALDH1A1 (0.34) | CA2HTR2CSLC6A4HTR2ACA1 | |
| SCHEMBL22013591 | 0.78 | CACNA1G (0.36) | CACNA1GCACNA1BCACNA1CRIPK1HTR2C | |
| SCHEMBL20680938 | 0.76 | CA2 (0.40) | CA2SLC6A4CA1CA12 | |
| SCHEMBL4029596 | 0.75 | HTR6 (0.37) | RIPK1HTR2CSLC6A4HTR2AGLS | |
| SCHEMBL22012131 | 0.75 | CACNA1G (0.34) | CACNA1GCACNA1BCACNA1CRIPK1CA2 | |
| SCHEMBL30244191 | 0.75 | HTR2C (0.38) | CACNA1GCACNA1BCACNA1CRIPK1CA2 | |
| SCHEMBL20692404 | 0.75 | HTR2C (0.38) | CACNA1GCACNA1BCACNA1CRIPK1CA2 | |
| SCHEMBL3654644 | 0.75 | HTR2C (0.38) | CA2HTR2CSLC6A4GLSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-16 | — | — | US | disclosed |
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | CACNA1G 3288/4885CACNA1B 2816/4885CACNA1C 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.