Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991051 | 0.77 | NLRP3 (0.35) | NLRP3MAPTL3MBTL1 | |
| Nibrozetone SCHEMBL2249018 | 0.77 | NLRP3 (0.47) | NLRP3MAPTL3MBTL1 | |
| SCHEMBL6365346 | 0.77 | ALDH1A1 (0.52) | NLRP3MAPTL3MBTL1 | |
| SCHEMBL21626535 | 0.73 | POLB (0.41) | L3MBTL1 | |
| SCHEMBL14841644 | 0.70 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL30787950 | 0.69 | JAK2 (0.31) | NLRP3 | |
| SCHEMBL1997904 | 0.67 | ESR1 (0.33) | NLRP3 | |
| SCHEMBL22015954 | 0.66 | NOS2 (0.34) | — | |
| SCHEMBL9347128 | 0.65 | L3MBTL1 (0.39) | NLRP3MAPTL3MBTL1 | |
| SCHEMBL31065659 | 0.65 | CASP3 (0.37) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008287-B2 | Sulfoxyalkyl organonitro and related compounds and pharmaceutical compounds for use in medicine | EPICENTRX, INC. (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200157047-A1 | SULFOXYALKYL ORGANONITRO AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOUNDS FOR USE IN MEDICINE | EPICENTRX, INC. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008287-B2 | Sulfoxyalkyl organonitro and related compounds and pharmaceutical compounds for use in medicine | AS3MT, SLC10A6, SLCO1B3 | NLRP3 1947/4885MAPT 1040/4885L3MBTL1 512/4885 |
| US-20200157047-A1 | SULFOXYALKYL ORGANONITRO AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOUNDS FOR USE IN MEDICINE | AS3MT, SLC10A6, SLCO1B3 | NLRP3 1947/4885MAPT 1040/4885L3MBTL1 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.