SCHEMBL22046138

SCHEMBL22046138

NCc1ccc(/C=C2\CCOc3cc(O)ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MIF P14174 5/20 0.49
▸ MAOB P27338 6/20 0.47
▸ MAOA P21397 5/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ CYP26A1 O43174 1/20 0.39
▸ ABAT P80404 1/20 0.38
▸ DYRK1A Q13627 2/20 0.37
▸ DYRK2 Q92630 2/20 0.37
▸ DYRK1B Q9Y463 2/20 0.37
▸ TYR P14679 1/20 0.37
▸ ESR1 P03372 1/20 0.36
▸ ESR2 Q92731 1/20 0.36
▸ APP P05067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22046626 0.74 MAOB (0.48) MIFMAOBMAOAKMT2AABAT
SCHEMBL22046148 0.69 MAOB (0.43) MAOBMAOAKMT2ATYR
SCHEMBL29837280 0.66 MIF (1.00) MIFMAOBMAOAKMT2ACYP26A1
SCHEMBL30251430 0.65 MAOB (1.00) MAOBMAOAESR2
SCHEMBL1091999 0.65 MAOB (1.00) MAOBMAOAESR2
SCHEMBL26777072 0.65 MAOA (0.64) MIFMAOBMAOACYP26A1ESR1
Water SCHEMBL15676351 0.64 MAOB (0.96) MAOBMAOAESR2
SCHEMBL6143494 0.64 ALDH1A1 (0.61) MIFMAOBMAOAKMT2ADYRK1A
SCHEMBL9490046 0.64 KMT2A (1.00) MIFMAOBKMT2ADYRK1ADYRK2
SCHEMBL6142893 0.64 ALDH1A1 (0.61) MIFMAOBMAOAKMT2ADYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 — — US disclosed
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 — — US disclosed
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2022-02-01 — — US disclosed
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION AAT BIOQUEST, INC. (US) 2020-12-03 — — US disclosed
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. 2020-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS MIF 3403/4885MAOB 272/4885MAOA 1625/4885
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS MIF 3403/4885MAOB 272/4885MAOA 1625/4885
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS MIF 3403/4885MAOB 272/4885MAOA 1625/4885
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION STUB1, SPR, HLCS MIF 3403/4885MAOB 272/4885MAOA 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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