Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | STK17B | O94768 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22046626 | 0.93 | MAOB (0.48) | MAOBSTK17BTYRMAOAMEN1 | |
| Isoaurostatin SCHEMBL15426107 | 0.72 | MAOA (0.63) | MAOBSTK17BTYRMAOAHDAC3 | |
| Isoaurostatin SCHEMBL29551912 | 0.72 | MAOA (0.63) | MAOBSTK17BTYRMAOAHDAC3 | |
| SCHEMBL5150290 | 0.70 | STK17B (0.56) | MAOBSTK17BMAOAHDAC3HDAC4 | |
| SCHEMBL22046138 | 0.69 | MIF (0.49) | MAOBTYRMAOAKMT2A | |
| SCHEMBL4165022 | 0.67 | NR3C1 (0.45) | MAOBMEN1KMT2ARAB9AAR | |
| SCHEMBL28305496 | 0.67 | LCK (0.51) | MEN1KMT2AUSP2 | |
| SCHEMBL13508455 | 0.67 | MIF (0.54) | MAOBSTK17BMAOAHDAC3HDAC4 | |
| SCHEMBL22731771 | 0.66 | MEN1 (0.31) | MAOBTYRMAOATOP1TOP2A | |
| SCHEMBL4261091 | 0.63 | TOP1 (0.75) | STK17BTYRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11821901-B2 | Styryl phenols, derivatives and their use in methods of analyte detection | AAT BIOQUEST, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11821901-B2 | Styryl phenols, derivatives and their use in methods of analyte detection | AAT BIOQUEST, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11237170-B2 | Styryl phenols, derivatives and their use in methods of analyte detection | AAT BIOQUEST, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-20200378975-A1 | STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION | AAT BIOQUEST, INC. (US) | 2020-12-03 | — | — | US | disclosed |
| US-20200174006-A1 | Styryl phenols, derivatives and their use in methods of analyte detection | AAT BIOQUEST, INC. | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11821901-B2 | Styryl phenols, derivatives and their use in methods of analyte detection | STUB1, SPR, HLCS | MAOB 272/4885STK17B 53/4885TYR 72/4885 |
| US-20200174006-A1 | Styryl phenols, derivatives and their use in methods of analyte detection | STUB1, SPR, HLCS | MAOB 272/4885STK17B 53/4885TYR 72/4885 |
| US-11237170-B2 | Styryl phenols, derivatives and their use in methods of analyte detection | STUB1, SPR, HLCS | MAOB 272/4885STK17B 53/4885TYR 72/4885 |
| US-20200378975-A1 | STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION | STUB1, SPR, HLCS | MAOB 272/4885STK17B 53/4885TYR 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.