Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11876083 | 0.88 | PTGS2 (0.62) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL17328820 | 0.80 | HSD17B10 (0.48) | MEN1KMT2AUSP2HSD17B10MAPT | |
| SCHEMBL2220181 | 0.79 | USP2 (0.47) | MEN1KMT2AUSP2HSD17B10MAPT | |
| SCHEMBL2220185 | 0.79 | USP2 (0.47) | MEN1KMT2AUSP2HSD17B10MAPT | |
| SCHEMBL8925967 | 0.78 | LMNA (0.75) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3880764 | 0.78 | LMNA (0.75) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL23321312 | 0.77 | LMNA (0.82) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL3115297 | 0.77 | LMNA (0.77) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL30139086 | 0.77 | LMNA (0.77) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL757098 | 0.77 | LMNA (0.77) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345541-B1 | Thermosensitive recording material and image recording method | RICOH CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2345541-A2 | Thermosensitive recording material and image recording method | Ricoh Company, Ltd. (JP) | 2011-07-20 | — | — | EP | disclosed |