Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.45 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.45 |
| ▸ | CA12 known ✓ | O43570 | 4/20 | 0.44 |
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.44 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17328820 | 0.91 | HSD17B10 (0.48) | USP2HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL3927939 | 0.90 | PTGS2 (0.52) | HSD17B10KMT2ATDP1CA12CA1 | |
| SCHEMBL11728809 | 0.90 | PTGS2 (0.52) | HSD17B10KMT2ATDP1CA12CA1 | |
| SCHEMBL2220185 | 0.90 | USP2 (0.47) | USP2HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL2206062 | 0.87 | P2RY12 (0.54) | USP2HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL14390759 | 0.85 | HSD17B10 (0.52) | USP2HSD17B10MEN1KMT2ATDP1 | |
| Potassium Ion SCHEMBL2219759 | 0.85 | P2RY12 (0.52) | P2RY2P2RY12CA12CA1CA2 | |
| Potassium Ion SCHEMBL2220070 | 0.84 | P2RY2 (0.51) | MEN1KMT2AP2RY2P2RY12CA12 | |
| SCHEMBL12994676 | 0.83 | HSD17B10 (0.49) | USP2HSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL8411922 | 0.82 | LMNA (0.60) | HSD17B10MEN1KMT2ATDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722190-A1 | Optimized undercoat for thermal recording material | Ricoh Industrie France SAS (FR) | 2014-04-23 | — | — | EP | disclosed |
| US-8546300-B2 | Thermosensitive recording material and image recording method | RICOH COMPANY, LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20110177941-A1 | THERMOSENSITIVE RECORDING MATERIAL AND IMAGE RECORDING METHOD | RICOH COMPANY, LTD. (JP) | 2011-07-21 | — | — | US | disclosed |