Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30599569 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL16241182 | 0.85 | CNR1 (0.42) | ALDH1A1KMT2ALMNACNR1CNR2 | |
| SCHEMBL30322440 | 0.83 | LMNA (0.41) | ALDH1A1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL3361445 | 0.83 | KMT2A (0.41) | ALDH1A1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL15834206 | 0.83 | CNR1 (0.41) | ALDH1A1KMT2ALMNAGAACNR1 | |
| SCHEMBL29801371 | 0.83 | KMT2A (0.41) | ALDH1A1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL29497605 | 0.81 | CNR1 (0.40) | ALDH1A1KMT2AL3MBTL1LMNACNR1 | |
| SCHEMBL240027 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL29679379 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL38657306 | 0.80 | KMT2A (0.38) | ALDH1A1KMT2AKDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595239-B2 | Substituted isoxazoline derivatives | BASF SE (DE) | 2026-04-07 | — | — | US | disclosed |
| EP-4291551-B1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2025-08-13 | — | — | EP | disclosed |
| US-20240140917-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2024-05-02 | — | — | US | disclosed |
| EP-4291551-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2023-12-20 | — | — | EP | disclosed |
| US-20230357210-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| US-20230357210-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| US-20230357210-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| CN-116888101-A | Substituted isoxazoline derivatives | 巴斯夫欧洲公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116529240-A | Nitrogen-containing condensed heterocyclic compound having oxime group, agrohorticultural herbicide containing the same and method of using the same | 日本农药株式会社 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022171472-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2022-08-18 | — | — | WO | disclosed |
| US-20150336946-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2015-11-26 | — | — | US | disclosed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| WO-2014099584-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2014-06-26 | — | — | WO | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8344003-B2 | 2-pyridinecarboxamide derivatives | MSD K. K. (JP) | 2013-01-01 | — | — | US | disclosed |
| EP-1598349-B1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD KK (JP) | 2011-07-27 | — | — | EP | disclosed |
| US-20100041660-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-7629362-B2 | 2-pyridine carboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | US | disclosed |
| EP-1598349-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595239-B2 | Substituted isoxazoline derivatives | CBR3, ADRA2C, CYP4Z1 | ALDH1A1 854/4885KMT2A 2132/4885KDM4E 3339/4885 |
| US-20150336946-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT | GCK, HK2, GCKR | ALDH1A1 1836/4885KMT2A 1231/4885KDM4E 841/4885 |
| US-20240140917-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | CYP4X1, PRDX5, PRDX1 | ALDH1A1 1168/4885KMT2A 2008/4885KDM4E 1605/4885 |
| US-20230357210-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | DDT, HDHD5, HPD | ALDH1A1 1952/4885KMT2A 664/4885KDM4E 1068/4885 |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | GCKR, GCK, HK2 | ALDH1A1 1207/4885KMT2A 1297/4885KDM4E 1304/4885 |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | GCKR, GCK, HK2 | ALDH1A1 1249/4885KMT2A 1311/4885KDM4E 1297/4885 |
| US-20100041660-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | GCKR, GCK, HK2 | ALDH1A1 1207/4885KMT2A 1297/4885KDM4E 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.