Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.72 |
| ▸ | AKT1 | P31749 | 3/20 | 0.72 |
| ▸ | CDC25A | P30304 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.59 |
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355527 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL28355399 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL28355525 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL10435761 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL4071722 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL6869674 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL1005430 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL769555 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL596158 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 | |
| SCHEMBL29067116 | 1.00 | AKT1 (0.72) | AKT1CDC25ALMNAESR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553126-B1 | STRETCHED RESIN FILM AND LABEL COMPRISING THE SAME | YUPO CORP (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-7981503-B2 | Good liquid absorbability with good seepage resistance; , dries within a short period of time and attains good adhesiveness when stuck to objects with a water-base adhesive | YUPO CORPORATION (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20050186371-A1 | Stretched resin film and label comprising the same | YUPO CORPORATION (JP) | 2005-08-25 | — | — | US | disclosed |
| EP-1553126-A1 | STRETCHED RESIN FILM AND LABEL COMPRISING THE SAME | Yupo Corporation (JP) | 2005-07-13 | — | — | EP | disclosed |