Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426306 | 0.91 | GPR119 (0.35) | ALDH1A1TSHRTRPV3GPR119 | |
| SCHEMBL2878291 | 0.91 | ALDH1A1 (0.35) | ALDH1A1HSD17B10LMNAKMT2ATSHR | |
| SCHEMBL1243493 | 0.89 | ALDH1A1 (0.40) | ALDH1A1HSD17B10LMNAKMT2ATSHR | |
| SCHEMBL2507025 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HSD17B10LMNAKMT2ATSHR | |
| SCHEMBL10091350 | 0.81 | TRPV3 (0.32) | ALDH1A1TRPV3L3MBTL1 | |
| SCHEMBL10091398 | 0.80 | TRPV3 (0.32) | TRPV3 | |
| SCHEMBL425880 | 0.80 | S1PR5 (0.38) | ALDH1A1LMNATSHRHTTCYP2C9 | |
| SCHEMBL4861841 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HSD17B10LMNAKMT2ATSHR | |
| SCHEMBL19066496 | 0.79 | ACACB (0.33) | — | |
| SCHEMBL9979284 | 0.78 | TLR4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580146-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20120193577-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| EP-1903090-B1 | Cyclohexene derivative having alkenyl, liquid crystal composition and liquid crystal display device | JNC CORP (JP) | 2011-07-27 | — | — | EP | disclosed |
| EP-1852429-B1 | Hexahydro dibenzofuran derivatives | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-1852429-B1 | Hexahydro dibenzofuran derivatives | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| US-7510749-B2 | Difluorobenzene derivative, alkenyl, cyclohexenyl; increased voltage holding ratio; high clearing point, low minimum temperature liquid crystal phase, enhanced temperature range of nematic phase; display device useful in wide temperature range; small viscosity, large elastic constant, fast response time | CHISSO CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7510749-B2 | Difluorobenzene derivative, alkenyl, cyclohexenyl; increased voltage holding ratio; high clearing point, low minimum temperature liquid crystal phase, enhanced temperature range of nematic phase; display device useful in wide temperature range; small viscosity, large elastic constant, fast response time | CHISSO CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7510749-B2 | Difluorobenzene derivative, alkenyl, cyclohexenyl; increased voltage holding ratio; high clearing point, low minimum temperature liquid crystal phase, enhanced temperature range of nematic phase; display device useful in wide temperature range; small viscosity, large elastic constant, fast response time | CHISSO CORPORATION (JP) | 2009-03-31 | — | — | US | disclosed |
| US-7417157-B2 | Hexahydrodibenzofuran derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417157-B2 | Hexahydrodibenzofuran derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1903090-A2 | Cyclohexene derivative having alkenyl, liquid crystal composition and liquid crystal display device | Chisso Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-1903090-A2 | Cyclohexene derivative having alkenyl, liquid crystal composition and liquid crystal display device | Chisso Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |
| US-20080063814-A1 | Difluorobenzene derivative, alkenyl, cyclohexenyl; increased voltage holding ratio; high clearing point, low minimum temperature liquid crystal phase, enhanced temperature range of nematic phase; display device useful in wide temperature range; small viscosity, large elastic constant, fast response time | CHISSO CORPORATION | 2008-03-13 | — | — | US | disclosed |
| US-20080063814-A1 | Difluorobenzene derivative, alkenyl, cyclohexenyl; increased voltage holding ratio; high clearing point, low minimum temperature liquid crystal phase, enhanced temperature range of nematic phase; display device useful in wide temperature range; small viscosity, large elastic constant, fast response time | CHISSO CORPORATION | 2008-03-13 | — | — | US | disclosed |
| US-20080063814-A1 | Difluorobenzene derivative, alkenyl, cyclohexenyl; increased voltage holding ratio; high clearing point, low minimum temperature liquid crystal phase, enhanced temperature range of nematic phase; display device useful in wide temperature range; small viscosity, large elastic constant, fast response time | CHISSO CORPORATION | 2008-03-13 | — | — | US | disclosed |
| EP-1852429-A1 | Hexahydro dibenzofuran derivatives | Merck Patent GmbH (DE) | 2007-11-07 | — | — | EP | disclosed |
| EP-1852429-A1 | Hexahydro dibenzofuran derivatives | Merck Patent GmbH (DE) | 2007-11-07 | — | — | EP | disclosed |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | MERCK PATENT GMBH | 2007-10-25 | — | — | US | disclosed |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | MERCK PATENT GMBH | 2007-10-25 | — | — | US | disclosed |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | MERCK PATENT GMBH | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080063814-A1 | Difluorobenzene derivative, alkenyl, cyclohexenyl; increased voltage holding ratio; high clearing point, low minimum temperature liquid crystal phase, enhanced temperature range of nematic phase; display device useful in wide temperature range; small viscosity, large elastic constant, fast response time | POU2F2, HCN2, POU2F1 | ALDH1A1 1701/4885HSD17B10 3170/4885LMNA 2345/4885 |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | HEXD, CFD, EDF1 | ALDH1A1 101/4885HSD17B10 790/4885LMNA 3018/4885 |
| US-20120193577-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | KIF23, MARK3, CCND3 | ALDH1A1 4082/4885HSD17B10 1669/4885LMNA 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.