SCHEMBL22129607

SCHEMBL22129607

CC(=CCCCc1ccccc1Oc1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.48
RIPK1 Q13546 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
FFAR1 O14842 1/20 0.42
PPARD Q03181 1/20 0.41
TSPO P30536 3/20 0.40
TBXAS1 P24557 1/20 0.40
P2RX3 P56373 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
PPARA Q07869 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
POLB P06746 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 1/20 0.38
SLC1A5 Q15758 1/20 0.38
CTNNB1 P35222 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129634 0.96 HRH1 (0.47) HRH1RIPK1SLC6A2SLC6A4FFAR1
SCHEMBL22129613 0.95 HRH1 (0.46) HRH1RIPK1SLC6A2SLC6A4FFAR1
SCHEMBL22129638 0.81 FFAR1 (0.53) FFAR1TBXAS1FFAR4
SCHEMBL26604646 0.79 GPR52 (0.49) RIPK1FFAR1PPARDTBXAS1FFAR4
SCHEMBL22129614 0.77 FDFT1 (0.49) FFAR1P2RX3FFAR4PPARA
SCHEMBL1624072 0.77 MTNR1A (0.54)
SCHEMBL22129594 0.77 FFAR1 (0.51) FFAR1TBXAS1FFAR4
SCHEMBL22129627 0.76 FFAR1 (0.50) FFAR1TBXAS1FFAR4
SCHEMBL22129595 0.76 FFAR1 (0.50) FFAR1TBXAS1FFAR4
SCHEMBL819986 0.75 L3MBTL1 (0.53) PPARATHRBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074945-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-07 US disclosed
EP-4268797-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION Kuraray Noritake Dental Inc. (JP) 2023-11-01 EP disclosed
US-20220218572-A1 DENTAL RESTORATIVE CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2022-07-14 US disclosed
US-11365280-B2 Photocurable resin composition KURARAY NORITAKE DENTAL INC. (JP) 2022-06-21 US disclosed
EP-3778681-A1 PHOTOCURABLE RESIN COMPOSITION Kuraray Noritake Dental Inc. (JP) 2021-02-17 EP disclosed
US-20210024682-A1 PHOTOCURABLE RESIN COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2021-01-28 US disclosed
WO-2020129736-A1 RESIN COMPOSITION FOR OPTICAL MOLDING クラレノリタケデンタル株式会社 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11365280-B2 Photocurable resin composition MAT1A, MAT2A, MAT2B HRH1 1897/4885RIPK1 1154/4885SLC6A2 4450/4885
US-20210024682-A1 PHOTOCURABLE RESIN COMPOSITION MAT1A, MAT2A, MAT2B HRH1 1897/4885RIPK1 1154/4885SLC6A2 4450/4885
US-20240074945-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION SMCHD1, WDR26, KAT6A HRH1 2370/4885RIPK1 1979/4885SLC6A2 4844/4885
US-20220218572-A1 DENTAL RESTORATIVE CURABLE COMPOSITION REV1, MMAB, WDR1 HRH1 2215/4885RIPK1 2913/4885SLC6A2 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.