Phenylalanine

Phenylalanine

SCHEMBL2214641

CC(C)CCCC(C)CCO.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
PTGS1 P23219 1/20 0.59
XIAP P98170 1/20 0.59
ANPEP P15144 3/20 0.50
RNPEP Q9H4A4 3/20 0.50
DNPEP Q9ULA0 3/20 0.50
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
LTA4H P09960 2/20 0.45
BLM P54132 1/20 0.44
SLC6A2 P23975 2/20 0.44
TAAR1 Q96RJ0 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
CYP2A6 P11509 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL2215770 0.89 SLC7A5 (0.67) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28229442 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL9226754 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8910300 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL37367 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL2063249 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6535507 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL3486837 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6033327 0.81 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL2214636 0.80 ANPEP (0.49) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130245246-A1 POLYSACCHARIDES COMPRISING CARBOXYL FUNCTIONAL GROUPS SUBSTITUTED BY A HYDROPHOBIC ALCOHOL DERIVATIVE ADOCIA (FR) 2013-09-19 US disclosed
US-8426382-B2 Polysaccharides comprising carboxyl functional groups substituted by a hydrophobic alcohol derivative ADOCIA (FR) 2013-04-23 US disclosed
US-20110178011-A1 Polysaccharide/BMP complexes which are soluble at physiological pH ADOCIA (FR) 2011-07-21 US disclosed
US-20100305035-A1 Polysaccharides comprising carboxyl functional groups substituted by a hydrophobic alcohol derivative ADOCIA (FR) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245246-A1 POLYSACCHARIDES COMPRISING CARBOXYL FUNCTIONAL GROUPS SUBSTITUTED BY A HYDROPHOBIC ALCOHOL DERIVATIVE CD44, B3GAT3, UGCG SLC7A5 211/4885ALPI 1476/4885PKM 3059/4885
US-20100305035-A1 Polysaccharides comprising carboxyl functional groups substituted by a hydrophobic alcohol derivative CD44, ADH1C, ADH5 SLC7A5 1345/4885ALPI 2359/4885PKM 2252/4885
US-20110178011-A1 Polysaccharide/BMP complexes which are soluble at physiological pH BMP1, BMP2, BMP6 SLC7A5 1111/4885ALPI 71/4885PKM 2000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.