Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2217031 | 0.76 | GABBR2 (0.38) | LMNAL3MBTL1CYP3A4CYP2D6NFKB1 | |
| SCHEMBL939692 | 0.68 | FABP4 (0.39) | KDM4ECA2LMNAL3MBTL1NAPRT | |
| SCHEMBL9722631 | 0.65 | CYP3A4 (0.36) | KDM4EHPGDKDM4CLMNAL3MBTL1 | |
| SCHEMBL940270 | 0.65 | AKR1B1 (0.38) | KDM4ECA2LMNAL3MBTL1NAPRT | |
| SCHEMBL28086991 | 0.64 | CYP2C9 (0.51) | FOLH1LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL2217027 | 0.64 | MEN1 (0.32) | ALDH1A1MAPK1NAPRT | |
| SCHEMBL2737360 | 0.63 | GABRA1 (0.37) | CA1CA2LMNA | |
| SCHEMBL10917742 | 0.63 | ALDH1A1 (0.47) | FOLH1CPB2KDM4EHPGDCPN1 | |
| SCHEMBL28107339 | 0.63 | CYP1A2 (0.48) | HPGDL3MBTL1ALDH1A1POLBCYP3A4 | |
| SCHEMBL8410187 | 0.62 | FFAR1 (0.44) | FFAR1AKR1C3AKR1C2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709046-B1 | P38 KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-07-27 | — | — | EP | disclosed |