Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643521 | 0.83 | KMO (0.43) | ALDH1A1LMNATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL134274 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL28489651 | 0.80 | ALDH1A1 (0.65) | ALDH1A1LMNACES2CES1TDP1 | |
| Benzophenone SCHEMBL1781970 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL13538244 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL29128530 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL134265 | 0.71 | CDC25B (0.55) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL22129542 | 0.70 | ALDH1A1 (0.56) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL12551615 | 0.69 | ALDH1A1 (0.50) | ALDH1A1CES2CES1TDP1L3MBTL1 | |
| SCHEMBL15264145 | 0.68 | MAPT (0.64) | ALDH1A1LMNATDP1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | ALDH1A1 1473/4885LMNA 4756/4885CES2 2468/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | ALDH1A1 1473/4885LMNA 4756/4885CES2 2468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.