Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12551413 | 1.00 | ALDH1A1 (0.45) | ALDH1A1LMNARAB9ANPC1HPGD | |
| SCHEMBL134215 | 0.93 | ALDH1A1 (0.52) | ALDH1A1LMNARAB9ANPC1HPGD | |
| SCHEMBL132902 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNARAB9ANPC1HPGD | |
| SCHEMBL15722840 | 0.87 | ALDH1A1 (0.61) | ALDH1A1LMNARAB9ANPC1HPGD | |
| SCHEMBL13780986 | 0.87 | L3MBTL1 (0.53) | ALDH1A1LMNARAB9ANPC1HPGD | |
| SCHEMBL13990422 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDCES2CES1 | |
| SCHEMBL12240221 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDCES2CES1 | |
| SCHEMBL13781015 | 0.84 | LMNA (0.47) | ALDH1A1LMNARAB9ANPC1HPGD | |
| SCHEMBL850988 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNARAB9ANPC1HPGD | |
| SCHEMBL13781088 | 0.84 | HPGD (0.63) | ALDH1A1LMNARAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | ALDH1A1 1473/4885LMNA 4756/4885RAB9A 2000/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | ALDH1A1 1473/4885LMNA 4756/4885RAB9A 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.