Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201368 | 0.87 | SYK (0.45) | GRM4CYP1A2MEN1KMT2ATGFBR1 | |
| SCHEMBL22201690 | 0.85 | CYP1A2 (0.31) | GRM4CYP1A2TGFBR1 | |
| SCHEMBL22201586 | 0.85 | PRKCH (0.47) | MEN1KMT2ATGFBR1SYKLMNA | |
| SCHEMBL22201286 | 0.84 | P2RX3 (0.40) | TGFBR1P2RX3ADORA3PRKD1SYK | |
| SCHEMBL22201226 | 0.83 | PRKCH (0.37) | GRM4CYP1A2TGFBR1P2RX3ADORA3 | |
| SCHEMBL22201273 | 0.83 | SYK (0.37) | GRM4CYP1A2MEN1KMT2ATGFBR1 | |
| SCHEMBL22201366 | 0.83 | MAPT (0.39) | CYP1A2MEN1KMT2ASYKLMNA | |
| SCHEMBL22201281 | 0.83 | SYK (0.36) | GRM4CYP1A2MEN1KMT2ATGFBR1 | |
| SCHEMBL22201225 | 0.83 | TGFBR1 (0.38) | GRM4CYP1A2TGFBR1P2RX3ADORA3 | |
| SCHEMBL22201224 | 0.83 | P2RX3 (0.42) | GRM4CYP1A2MEN1KMT2ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |