Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201223 | 0.85 | GRM4 (0.38) | CYP1A2GRM4TGFBR1 | |
| SCHEMBL22201225 | 0.83 | TGFBR1 (0.38) | CYP1A2GRM4TGFBR1 | |
| SCHEMBL22201226 | 0.76 | PRKCH (0.37) | CYP1A2GRM4TGFBR1 | |
| SCHEMBL22201366 | 0.74 | MAPT (0.39) | CYP1A2 | |
| SCHEMBL22201586 | 0.74 | PRKCH (0.47) | TGFBR1 | |
| SCHEMBL22201368 | 0.74 | SYK (0.45) | CYP1A2GRM4TGFBR1 | |
| SCHEMBL22201489 | 0.74 | SYK (0.37) | CYP1A2GRM4TGFBR1 | |
| SCHEMBL22201536 | 0.74 | ACP1 (0.36) | CYP1A2GRM4TGFBR1 | |
| SCHEMBL22201324 | 0.73 | ADORA3 (0.39) | CYP1A2GRM4TGFBR1 | |
| SCHEMBL22201531 | 0.73 | ABL1 (0.38) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |