Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201238 | 0.92 | POLB (0.36) | ABCG2MAPTP2RX3ALDH1A1 | |
| SCHEMBL22201242 | 0.86 | HTR2C (0.38) | ABCG2P2RX3ALDH1A1ABCB1 | |
| SCHEMBL22201321 | 0.84 | BRAF (0.36) | ABCG2P2RX3ABCB1 | |
| SCHEMBL22201653 | 0.81 | TGFBR1 (0.41) | ABCG2P2RX3ALDH1A1ABCB1ABCC1 | |
| SCHEMBL22201481 | 0.81 | CSF1R (0.37) | ABCG2MAPTP2RX3ALDH1A1ABCB1 | |
| SCHEMBL22201368 | 0.75 | SYK (0.45) | ABCG2P2RX3ALDH1A1ABCB1 | |
| SCHEMBL22201273 | 0.74 | SYK (0.37) | MAPTP2RX3ALDH1A1 | |
| SCHEMBL22201366 | 0.74 | MAPT (0.39) | ABCG2MAPTHTTALDH1A1L3MBTL1 | |
| SCHEMBL22201537 | 0.74 | KDM4E (0.42) | MAPTP2RX3ALDH1A1 | |
| SCHEMBL22201586 | 0.74 | PRKCH (0.47) | ABCG2MAPTALDH1A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |