Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201321 | 0.90 | BRAF (0.36) | TGFBR1PRKD1ABCB1ABCG2ADORA3 | |
| SCHEMBL22201242 | 0.88 | HTR2C (0.38) | TGFBR1PRKD1ABCB1ABCG2ALOX12 | |
| SCHEMBL22201238 | 0.83 | POLB (0.36) | TGFBR1ABCG2ALDH1A1P2RX3LMNA | |
| SCHEMBL22201481 | 0.81 | CSF1R (0.37) | ABCB1ABCG2ADORA3ALDH1A1P2RX3 | |
| SCHEMBL22201243 | 0.81 | ABCG2 (0.35) | ABCB1ABCG2ALDH1A1P2RX3ABCC1 | |
| SCHEMBL22201368 | 0.78 | SYK (0.45) | TGFBR1PRKD1ABCB1ABCG2ADORA3 | |
| SCHEMBL22201415 | 0.76 | PIP4K2A (0.37) | TGFBR1PRKD1ALOX12ALDH1A1P2RX3 | |
| SCHEMBL22201223 | 0.75 | GRM4 (0.38) | TGFBR1PRKD1ADORA3ALOX12ALDH1A1 | |
| SCHEMBL22201586 | 0.75 | PRKCH (0.47) | TGFBR1ABCB1ABCG2ALDH1A1ROCK2 | |
| SCHEMBL22201537 | 0.75 | KDM4E (0.42) | TGFBR1ADORA3ALDH1A1P2RX3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |