Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201243 | 0.92 | ABCG2 (0.35) | ALDH1A1P2RX3ABCG2MAPT | |
| SCHEMBL22201242 | 0.84 | HTR2C (0.38) | ALDH1A1MEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL22201653 | 0.83 | TGFBR1 (0.41) | ALDH1A1SMN1; SMN2TGFBR1P2RX3ABCG2 | |
| SCHEMBL22201321 | 0.81 | BRAF (0.36) | MEN1KMT2ATGFBR1P2RX3ABCG2 | |
| SCHEMBL22201481 | 0.78 | CSF1R (0.37) | ALDH1A1MEN1KMT2AP2RX3ABCG2 | |
| SCHEMBL22201368 | 0.73 | SYK (0.45) | ALDH1A1MEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL22201415 | 0.72 | PIP4K2A (0.37) | ALDH1A1MEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL22201366 | 0.71 | MAPT (0.39) | ALDH1A1MEN1KMT2AABCG2MAPT | |
| SCHEMBL22201223 | 0.71 | GRM4 (0.38) | ALDH1A1MEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL22201537 | 0.71 | KDM4E (0.42) | POLBALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |