Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 7/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201322 | 0.87 | PIP4K2C (0.34) | P2RX3TGFBR1JAK2TYK2JAK3 | |
| SCHEMBL22201607 | 0.86 | RIPK2 (0.39) | TGFBR1PRKD1ALDH1A1ALOX12 | |
| SCHEMBL22201262 | 0.86 | RIPK2 (0.36) | P2RX3TGFBR1ALDH1A1JAK2TYK2 | |
| SCHEMBL22201493 | 0.85 | ROCK2 (0.34) | P2RX3TGFBR1PRKD1METPIK3CD | |
| SCHEMBL22201534 | 0.84 | PIK3CD (0.40) | TGFBR1JAK2TYK2JAK3PIK3CD | |
| SCHEMBL22201368 | 0.83 | SYK (0.45) | P2RX3TGFBR1PRKD1ALDH1A1ALOX12 | |
| SCHEMBL22201423 | 0.83 | TRPV1 (0.41) | — | |
| SCHEMBL22201366 | 0.81 | MAPT (0.39) | ALDH1A1 | |
| SCHEMBL22201586 | 0.81 | PRKCH (0.47) | TGFBR1ALDH1A1 | |
| SCHEMBL22201286 | 0.81 | P2RX3 (0.40) | P2RX3TGFBR1PRKD1ALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |