Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201262 | 0.89 | RIPK2 (0.36) | RIPK2KDRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22201534 | 0.87 | PIK3CD (0.40) | RIPK2KDRTGFBR1PIP4K2APIP4K2C | |
| SCHEMBL22201493 | 0.87 | ROCK2 (0.34) | PRKD1TGFBR1SYK | |
| SCHEMBL22201425 | 0.86 | P2RX3 (0.36) | PRKD1ALDH1A1ALOX12TGFBR1 | |
| SCHEMBL22201286 | 0.86 | P2RX3 (0.40) | KDRPRKD1ALDH1A1ALOX12TP53 | |
| SCHEMBL22201368 | 0.85 | SYK (0.45) | PRKD1ALDH1A1ALOX12TGFBR1SYK | |
| SCHEMBL22201322 | 0.84 | PIP4K2C (0.34) | TGFBR1PIP4K2APIP4K2C | |
| SCHEMBL22201271 | 0.83 | SYK (0.38) | PRKD1ALDH1A1TSHRTGFBR1SYK | |
| SCHEMBL22201366 | 0.81 | MAPT (0.39) | ALDH1A1LMNATSHRSYK | |
| SCHEMBL22201586 | 0.81 | PRKCH (0.47) | ALDH1A1LMNASMN1; SMN2TGFBR1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |