Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137944 | 0.81 | CCR4 (0.41) | CCR4 | |
| SCHEMBL27146171 | 0.77 | CCR4 (0.33) | CCR4 | |
| SCHEMBL23569421 | 0.76 | CCR4 (0.38) | CCR4 | |
| SCHEMBL2888207 | 0.67 | GSK3B (0.36) | — | |
| SCHEMBL1926045 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL6432730 | 0.67 | — | — | |
| SCHEMBL23531868 | 0.65 | — | — | |
| SCHEMBL23531805 | 0.65 | — | — | |
| SCHEMBL1177826 | 0.62 | — | — | |
| SCHEMBL3037140 | 0.62 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2021-03-25 | — | — | US | claimed |
| EP-2544535-B1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIV (US) | 2017-04-19 | — | — | EP | claimed |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2016-08-18 | — | — | US | claimed |
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-12-26 | — | — | US | claimed |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2013-12-26 | — | — | US | claimed |
| EP-2544535-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | North Carolina Central University (US) | 2013-01-16 | — | — | EP | claimed |
| WO-2011112858-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-09-15 | — | — | WO | claimed |
| WO-2011084503-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-07-14 | — | — | WO | claimed |
| CN-117177975-B | Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | UNIVERSITE DE MONTREAL (CA) | 2025-11-25 | — | — | US | disclosed |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2025-08-28 | — | — | US | disclosed |
| US-12247004-B2 | 2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use | Oxford Drug Design Limited (GB) | 2025-03-11 | — | — | US | disclosed |
| CN-114846000-B | 2-Amino-N- (amino-oxo-aryl-lambda 6-sulfinyl) acetamide compounds and therapeutic uses thereof | 牛津药物设计有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | Université de Montréal (CA) | 2024-11-12 | — | — | US | disclosed |
| CN-1492863-A | Heterocyclylalkyl-indole or azaindole compounds as 5-hydroxytryptamine-6 ligands | — | 2004-04-28 | — | — | CN | disclosed |
| US-20030225121-A1 | Heterocyclylalkylindole or-azaindole compounds as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2003-12-04 | — | — | US | disclosed |
| EP-1355900-A2 | HETEROCYCLYLALKYLINDOLE OR -AZAINDOLE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6613781-B2 | Potential use in the treatment of a variety of central nervous system disorders such as anxiety, depression, epilepsy, obsessive-compulsive disorders, migraine, congnitive disorders, sleep disorders and schizophrenia | WYETH | 2003-09-02 | — | — | US | disclosed |
| US-20020128477-A1 | Heterocyclylalkylindole or -azaindole compounds as 5-hydroxytryptamine-6 ligands | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-09-12 | — | — | US | disclosed |
| WO-2002051832-A2 | HETEROCYCLYLALKYLINDOLE OR -AZAINDOLE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12247004-B2 | 2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use | AARS1, ASNS, GARS1 | CCR4 3982/4885 |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | CCR4 1777/4885 |
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | CES2, TOP1, GUSB | CCR4 3136/4885 |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | CCR4 3898/4885 |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, TOP2B | CCR4 3972/4885 |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, KRAS | CCR4 1777/4885 |
| US-20020128477-A1 | Heterocyclylalkylindole or -azaindole compounds as 5-hydroxytryptamine-6 ligands | HTR6, HTR5A, HTR1A | CCR4 2298/4885 |
| US-20030225121-A1 | Heterocyclylalkylindole or-azaindole compounds as 5-hydroxytryptamine-6 ligands | HTR6, HTR5A, HTR1A | CCR4 2298/4885 |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, DPYD | CCR4 1812/4885 |
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | CCR4 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.