Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205496 | 0.81 | L3MBTL1 (0.41) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL18949030 | 0.78 | DGAT2 (0.38) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL10120015 | 0.77 | DGAT2 (0.37) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL7914435 | 0.75 | SMN1; SMN2 (0.41) | ADORA3ADORA2AADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17513474 | 0.72 | NOS1 (0.39) | ADORA2AADORA1ALDH1A1SMN1; SMN2NOS1 | |
| SCHEMBL11916062 | 0.72 | NUDT1 (0.55) | SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL15935288 | 0.72 | L3MBTL1 (0.36) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL9406894 | 0.69 | ADORA1 (0.51) | L3MBTL1ADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL10140811 | 0.69 | HSD17B10 (0.43) | ADORA3ADORA2AADORA1ALDH1A1NOS1 | |
| SCHEMBL8312963 | 0.69 | NOS1 (0.44) | L3MBTL1ADORA2AADORA1NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231547-A1 | 2-(1,1'-BIPHENYL)-1H-BENZODIMIDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS APELIN AND APJ AGONISTS FOR TREATING CARDIOVASCULAR DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231547-A1 | 2-(1,1'-BIPHENYL)-1H-BENZODIMIDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS APELIN AND APJ AGONISTS FOR TREATING CARDIOVASCULAR DISEASES | APLNR, AP3B1, AP2B1 | DGAT2 2104/4885L3MBTL1 3605/4885ADORA3 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.