Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22244252 | 0.78 | DGAT2 (0.39) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL12205496 | 0.78 | L3MBTL1 (0.41) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL12231815 | 0.76 | DDAH1 (0.48) | L3MBTL1ADORA3ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL10120015 | 0.74 | DGAT2 (0.37) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL25833558 | 0.71 | HSD17B10 (0.41) | ADORA3ADORA2AADORA1ALDH1A1DDAH1 | |
| SCHEMBL11916062 | 0.69 | NUDT1 (0.55) | SMN1; SMN2 | |
| SCHEMBL15935288 | 0.69 | L3MBTL1 (0.36) | DGAT2L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL868599 | 0.69 | SMN1; SMN2 (0.43) | L3MBTL1ALDH1A1SMN1; SMN2SCN10AKCNH2 | |
| SCHEMBL12438210 | 0.68 | HTT (0.44) | L3MBTL1ADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL12438207 | 0.68 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2SCN10AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |