Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22233284 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6507499 | 0.84 | LMNA (0.49) | ALDH1A1CYP2C9CYP2C19LMNANPC1 | |
| SCHEMBL22233863 | 0.81 | CA2 (0.39) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL3603475 | 0.81 | ALDH1A3 (0.42) | KDM4EALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL1931571 | 0.81 | ALDH1A3 (0.42) | KDM4EALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL22254863 | 0.80 | AR (0.34) | AAK1 | |
| SCHEMBL254987 | 0.80 | MAPT (0.55) | ALDH1A1HPGDMAPTPOLBLMNA | |
| SCHEMBL30276604 | 0.79 | APLNR (0.30) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL27244222 | 0.79 | PARP10 (0.49) | ALDH1A1MAPTPOLBLMNATSHR | |
| SCHEMBL27243795 | 0.77 | MAPT (0.51) | ALDH1A1MAPTPOLBLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |