Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22233863 | 0.83 | CA2 (0.39) | APLNRKDM4EALDH1A1POLBMAPT | |
| SCHEMBL30276657 | 0.81 | — | — | |
| SCHEMBL22249309 | 0.79 | KDM4E (0.36) | APLNRKDM4EALDH1A1POLBMAPT | |
| SCHEMBL22233284 | 0.79 | ALDH1A1 (0.43) | APLNRKDM4EALDH1A1POLBMAPT | |
| SCHEMBL6507499 | 0.78 | LMNA (0.49) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1931571 | 0.75 | ALDH1A3 (0.42) | KDM4EALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL3603475 | 0.75 | ALDH1A3 (0.42) | KDM4EALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL254987 | 0.74 | MAPT (0.55) | ALDH1A1POLBMAPTHPGD | |
| SCHEMBL27244222 | 0.73 | PARP10 (0.49) | ALDH1A1POLBMAPT | |
| SCHEMBL27243795 | 0.72 | MAPT (0.51) | ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503452-B2 | Antimicrobial compounds and methods | CURZA GLOBAL, LLC (US) | 2025-12-23 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230072397-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | APLNR 2740/4885KDM4E 3027/4885ALDH1A1 3752/4885 |
| US-20230072397-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | APLNR 2740/4885KDM4E 3027/4885ALDH1A1 3752/4885 |
| US-12503452-B2 | Antimicrobial compounds and methods | MPO, NISCH, RPN2 | APLNR 2740/4885KDM4E 3027/4885ALDH1A1 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.