Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22258475 | 0.87 | NPC1 (0.49) | RAB9ANPC1MAPTRECQLVNN1 | |
| SCHEMBL22258549 | 0.83 | LTA4H (0.47) | RAB9ANPC1HTTKDM4EKDM6B | |
| SCHEMBL22258246 | 0.77 | NOS1 (0.40) | RAB9ANPC1MAPTRECQLNOS2 | |
| SCHEMBL22258552 | 0.77 | LTA4H (0.48) | MAPTKDM4EKDR | |
| SCHEMBL22236040 | 0.75 | FLT1 (0.42) | MAPTKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL22236103 | 0.74 | DDR1 (0.44) | RAB9ANPC1MAPTHTTFLT1 | |
| SCHEMBL22258553 | 0.74 | HSD17B10 (0.40) | HTTKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL22258560 | 0.74 | RAB9A (0.42) | RAB9ANPC1MAPTRECQLHTT | |
| SCHEMBL22258481 | 0.73 | EGFR (0.55) | RAB9ANPC1MAPTFLT1KDR | |
| SCHEMBL22258247 | 0.73 | CDK5 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |