Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 3/20 | 0.36 |
| ▸ | CDK8 | P49336 | 3/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11957361 | 0.84 | SMN1; SMN2 (0.49) | CSNK1A1MAPTKDM4EALDH1A1CDK8 | |
| SCHEMBL19039326 | 0.75 | SMN1; SMN2 (0.36) | HASPINKDM4EPOLBSMN1; SMN2HPGD | |
| SCHEMBL15186271 | 0.72 | LMNA (0.40) | MAPTPOLBALDH1A1CCNCCDK8 | |
| SCHEMBL22258956 | 0.71 | ROCK2 (0.44) | CSNK1DMAPK1AXL | |
| SCHEMBL22258784 | 0.70 | TSHR (0.36) | MAPK1POLBALDH1A1CDC7NPSR1 | |
| SCHEMBL5451902 | 0.70 | IMPDH2 (0.44) | CSNK1DCLK2MAPTMAPK1CDK2 | |
| SCHEMBL22258786 | 0.70 | CSNK2A2 (0.48) | — | |
| SCHEMBL1846920 | 0.69 | ALDH1A1 (0.49) | MAPTKDM4EPOLBALDH1A1L3MBTL1 | |
| SCHEMBL7729548 | 0.69 | KDM4E (0.50) | MAPTKDM4EPOLBALDH1A1L3MBTL1 | |
| SCHEMBL415485 | 0.69 | KDM4E (0.55) | MAPTKDM4EPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |