Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18448352 | 0.77 | CYP2D6 (0.37) | EPHX1EPHX2NPC1RAB9A | |
| SCHEMBL22270867 | 0.75 | WNT3A (0.32) | NPC1RAB9A | |
| SCHEMBL22270591 | 0.75 | PSMB5 (0.33) | — | |
| SCHEMBL22271072 | 0.71 | WNT3A (0.38) | — | |
| SCHEMBL22271075 | 0.70 | RXRA (0.31) | — | |
| SCHEMBL22270887 | 0.70 | KDM4E (0.40) | ACACBROCK2 | |
| SCHEMBL18448135 | 0.68 | HIF1A (0.46) | HIF1AUTS2RSYKGRM4 | |
| SCHEMBL22270563 | 0.68 | WNT3A (0.39) | NPC1 | |
| SCHEMBL22270601 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL22270880 | 0.66 | LMNA (0.37) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |