Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270887 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1GAAHPGDL3MBTL1 | |
| SCHEMBL22270563 | 0.77 | WNT3A (0.39) | KDM4ERORC | |
| SCHEMBL22270591 | 0.76 | PSMB5 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL22270880 | 0.75 | LMNA (0.37) | ALDH1A1 | |
| SCHEMBL19205760 | 0.74 | PSMB5 (0.41) | GAARORC | |
| SCHEMBL19205757 | 0.74 | PSMB5 (0.41) | GAARORC | |
| SCHEMBL22270547 | 0.73 | TRPV1 (0.34) | — | |
| SCHEMBL22270671 | 0.72 | RORC (0.39) | RORC | |
| SCHEMBL22270668 | 0.72 | KDR (0.36) | ALDH1A1GAAHPGDRORC | |
| SCHEMBL21796354 | 0.72 | SMN1; SMN2 (0.40) | GAARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |