Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270537 | 0.89 | MAPT (0.36) | WNT3ADGAT1KDRPDE10AMEN1 | |
| SCHEMBL22270880 | 0.89 | LMNA (0.37) | WNT3AKDRMEN1KMT2ALMNA | |
| SCHEMBL22270671 | 0.85 | RORC (0.39) | WNT3AKDRPDE10ARORCHTT | |
| SCHEMBL22270885 | 0.84 | RORC (0.35) | KDRPDE10ARORCLMNAMAPT | |
| SCHEMBL22270668 | 0.83 | KDR (0.36) | WNT3AKDRPDE10ARORCMEN1 | |
| SCHEMBL22271066 | 0.82 | RORC (0.35) | RORCMAPT | |
| SCHEMBL22271062 | 0.81 | LPAR1 (0.35) | KDRRORC | |
| SCHEMBL22271048 | 0.80 | PDGFRB (0.41) | WNT3ALMNAMAPTTP53KDM4E | |
| SCHEMBL22270887 | 0.79 | KDM4E (0.40) | MAPTKDM4EHTT | |
| SCHEMBL18485956 | 0.79 | WNT3A (0.35) | WNT3APDE10ARORCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |