Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270563 | 0.89 | WNT3A (0.39) | LMNATP53MAPTNPC1KDR | |
| SCHEMBL22270537 | 0.82 | MAPT (0.36) | LMNATP53MAPTNPC1RAB9A | |
| SCHEMBL22271066 | 0.80 | RORC (0.35) | MAPTNAMPT | |
| SCHEMBL22270668 | 0.79 | KDR (0.36) | LMNAMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL22271048 | 0.78 | PDGFRB (0.41) | LMNATP53MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL22270885 | 0.78 | RORC (0.35) | LMNATP53MAPTRAB9AALDH1A1 | |
| SCHEMBL22270603 | 0.78 | MAPT (0.35) | LMNATP53MAPT | |
| SCHEMBL22270671 | 0.77 | RORC (0.39) | SMN1; SMN2KDRPSMB5WNT3A | |
| SCHEMBL22270887 | 0.77 | KDM4E (0.40) | MAPTALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL22270601 | 0.75 | KDM4E (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |