Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22284683 | 0.79 | APP (0.30) | APPMAPT | |
| SCHEMBL22284650 | 0.78 | PKM (0.39) | MAPT | |
| SCHEMBL22708302 | 0.77 | NOS2 (0.33) | — | |
| SCHEMBL22299197 | 0.69 | FBP1 (0.40) | MAPT | |
| SCHEMBL22284769 | 0.64 | KDM4E (0.32) | MAPT | |
| SCHEMBL20843914 | 0.62 | — | — | |
| SCHEMBL21737386 | 0.59 | — | — | |
| SCHEMBL22235052 | 0.58 | KDM4E (0.39) | — | |
| Hydrochloric Acid SCHEMBL22834733 | 0.58 | — | — | |
| SCHEMBL21719950 | 0.56 | KDM4E (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548873-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-10 | — | — | US | claimed |
| US-20210078979-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-18 | — | — | US | claimed |
| US-10882846-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-05 | — | — | US | claimed |
| US-20200247782-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-06 | — | — | US | claimed |
| EP-3921307-B1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-26 | — | — | EP | disclosed |
| US-11851420-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-12-26 | — | — | US | disclosed |
| US-20230114845-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-13 | — | — | US | disclosed |
| US-11548873-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-10 | — | — | US | disclosed |
| US-10947219-B2 | Enantioselective process for the manufacture of lactam carboxylate derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-10851085-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-01 | — | — | US | disclosed |
| US-10800759-B2 | — | — | 2020-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851420-B2 | Pyrazole derivatives | RB1, CBR3, CYP1B1 | APP 4265/4885MAPT 3022/4885 |
| US-10882846-B2 | Pyrazole derivatives | RB1, CBR3, CYP1B1 | APP 4265/4885MAPT 3022/4885 |
| US-10851085-B2 | Pyrazole derivatives | RB1, RBBP5, RBBP7 | APP 4240/4885MAPT 2888/4885 |
| US-20200247782-A1 | PYRAZOLE DERIVATIVES | RB1, CBR3, CYP1B1 | APP 4265/4885MAPT 3022/4885 |
| US-10947219-B2 | Enantioselective process for the manufacture of lactam carboxylate derivatives | UBE2D3, SBDS, MRPL21 | APP 3556/4885MAPT 4228/4885 |
| US-20230114845-A1 | PYRAZOLE DERIVATIVES | RB1, CBR3, CYP1B1 | APP 4265/4885MAPT 3022/4885 |
| US-20210078979-A1 | PYRAZOLE DERIVATIVES | RB1, CBR3, CYP1B1 | APP 4265/4885MAPT 3022/4885 |
| US-11548873-B2 | Pyrazole derivatives | RB1, CBR3, CYP1B1 | APP 4265/4885MAPT 3022/4885 |
| US-10800759-B2 | — | RB1, RBBP5, CCNC | APP 3924/4885MAPT 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.