Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 13/20 | 0.40 |
| ▸ | VCP | P55072 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ABL2 | P42684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22298846 | 0.80 | FBP1 (0.40) | FBP1VCPALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22284469 | 0.80 | FBP1 (0.41) | FBP1VCPMEN1PSMD14KMT2A | |
| SCHEMBL22708302 | 0.74 | NOS2 (0.33) | — | |
| SCHEMBL8638984 | 0.72 | FBP1 (0.42) | FBP1VCPMEN1KMT2AALDH1A1 | |
| SCHEMBL8551772 | 0.72 | FBP1 (0.42) | FBP1VCPMEN1KMT2AALDH1A1 | |
| SCHEMBL22284696 | 0.69 | APP (0.30) | MAPT | |
| SCHEMBL22298844 | 0.67 | MEN1 (0.40) | FBP1VCPMEN1PSMD14KMT2A | |
| SCHEMBL25420525 | 0.66 | ALDH1A1 (0.40) | FBP1VCPMEN1KMT2AALDH1A1 | |
| SCHEMBL25420528 | 0.66 | ALDH1A1 (0.40) | FBP1VCPMEN1KMT2AALDH1A1 | |
| SCHEMBL28994128 | 0.65 | FBP1 (0.39) | FBP1MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921307-B1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-26 | — | — | EP | disclosed |
| US-11548873-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-10 | — | — | US | disclosed |
| US-20210078979-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-18 | — | — | US | disclosed |
| US-10947219-B2 | Enantioselective process for the manufacture of lactam carboxylate derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-10882846-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-05 | — | — | US | disclosed |
| US-10865197-B2 | Enantioselective process for manufacture | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-15 | — | — | US | disclosed |
| US-10851085-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-01 | — | — | US | disclosed |
| US-10800759-B2 | — | — | 2020-10-13 | — | — | US | disclosed |
| US-20200283409-A1 | Pyrazole Derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2020-09-10 | — | — | US | disclosed |
| US-20200283410-A1 | Enantioselective Process For The Manufacture Of Lactam Carboxylate Derivatives | SYNGENTA CROP PROTECTION AG (GB) | 2020-09-10 | — | — | US | disclosed |
| US-20200283411-A1 | Enantioselective Process For Manufacture | SYNGENTA CROP PROTECTION AG (CH) | 2020-09-10 | — | — | US | disclosed |
| US-20200247782-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283409-A1 | Pyrazole Derivatives | RB1, RBBP5, RBBP4 | FBP1 1738/4885VCP 4216/4885MEN1 1399/4885 |
| US-10882846-B2 | Pyrazole derivatives | RB1, CBR3, CYP1B1 | FBP1 1277/4885VCP 2745/4885MEN1 2563/4885 |
| US-10851085-B2 | Pyrazole derivatives | RB1, RBBP5, RBBP7 | FBP1 1877/4885VCP 3890/4885MEN1 1667/4885 |
| US-20200283410-A1 | Enantioselective Process For The Manufacture Of Lactam Carboxylate Derivatives | UBE2D3, SBDS, MRPL21 | FBP1 1445/4885VCP 3655/4885MEN1 1801/4885 |
| US-20200247782-A1 | PYRAZOLE DERIVATIVES | RB1, CBR3, CYP1B1 | FBP1 1277/4885VCP 2745/4885MEN1 2563/4885 |
| US-10947219-B2 | Enantioselective process for the manufacture of lactam carboxylate derivatives | UBE2D3, SBDS, MRPL21 | FBP1 1445/4885VCP 3655/4885MEN1 1801/4885 |
| US-10865197-B2 | Enantioselective process for manufacture | RB1, RBX1, RBBP4 | FBP1 1586/4885VCP 2085/4885MEN1 1029/4885 |
| US-20200283411-A1 | Enantioselective Process For Manufacture | RB1, RBX1, RBBP4 | FBP1 1586/4885VCP 2085/4885MEN1 1029/4885 |
| US-20210078979-A1 | PYRAZOLE DERIVATIVES | RB1, CBR3, CYP1B1 | FBP1 1277/4885VCP 2745/4885MEN1 2563/4885 |
| US-11548873-B2 | Pyrazole derivatives | RB1, CBR3, CYP1B1 | FBP1 1277/4885VCP 2745/4885MEN1 2563/4885 |
| US-10800759-B2 | — | RB1, RBBP5, CCNC | FBP1 3240/4885VCP 2853/4885MEN1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.