SCHEMBL22299758

SCHEMBL22299758

CCCC(CCC)C(=O)N1CCN(CCNC(=O)OC(C)(C)C)CC1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.53
DRD2 P14416 7/20 0.48
CACNA1H O95180 1/20 0.47
TSHR P16473 1/20 0.45
SIGMAR1 Q99720 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
GAA P10253 1/20 0.45
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
HRH2 P25021 2/20 0.41
HRH1 P35367 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
USP2 O75604 1/20 0.40
CD274 Q9NZQ7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301242 0.82 DRD2 (0.63) DRD2CACNA1HSIGMAR1MEN1KMT2A
SCHEMBL18713085 0.82 CACNA1H (0.52) DRD2CACNA1HTSHRSIGMAR1MEN1
SCHEMBL20857027 0.81 CYP2C19 (0.61) CYP2C19TSHRMEN1KMT2AGAA
SCHEMBL15859325 0.80 DRD2 (0.55) CYP2C19DRD2CACNA1HSIGMAR1TDP1
SCHEMBL18390128 0.80 DRD2 (0.57) DRD2CACNA1HSIGMAR1MEN1KMT2A
SCHEMBL18824244 0.79 DRD2 (0.54) DRD2CACNA1HSIGMAR1TDP1CD274
SCHEMBL8406122 0.79 DRD2 (0.54) DRD2CACNA1HSIGMAR1MEN1KMT2A
SCHEMBL13202614 0.78 DRD2 (0.59) DRD2CACNA1HSIGMAR1MEN1KMT2A
SCHEMBL30380480 0.77 TDP1 (0.59) DRD2CACNA1HSIGMAR1MEN1KMT2A
SCHEMBL5324032 0.77 DRD2 (0.57) DRD2CACNA1HSIGMAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12599599-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2026-04-14 US disclosed
EP-4578508-A2 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF Medicon Pharmaceuticals, Inc. (US) 2025-07-02 EP disclosed
EP-3687972-B1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS INC (US) 2025-04-09 EP disclosed
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. 2024-01-18 US disclosed
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. 2024-01-18 US disclosed
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. 2024-01-18 US disclosed
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2023-09-12 US disclosed
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2023-09-12 US disclosed
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2023-09-12 US disclosed
US-20200246330-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. (US) 2020-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599599-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof VEGFA, SLC10A6, LITAF CYP2C19 978/4885DRD2 2418/4885CACNA1H 831/4885
US-20200246330-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF VEGFA, HPGDS, ALOX5 CYP2C19 666/4885DRD2 2058/4885CACNA1H 4823/4885
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof VEGFA, HPGDS, ALOX5 CYP2C19 666/4885DRD2 2058/4885CACNA1H 4823/4885
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF VEGFA, HPGDS, ALOX5 CYP2C19 666/4885DRD2 2058/4885CACNA1H 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.