Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559689 | 0.90 | CYP1A2 (0.37) | KDM4EALDH1A1HPGDMAPK1ALOX15 | |
| SCHEMBL2241715 | 0.80 | MAPT (0.35) | MAPT | |
| SCHEMBL3614160 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL343340 | 0.76 | CA12 (0.34) | — | |
| SCHEMBL1978423 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL341251 | 0.73 | PAX8 (0.35) | — | |
| SCHEMBL7168637 | 0.72 | MAPT (0.38) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15331328 | 0.71 | KCNH2 (0.31) | — | |
| SCHEMBL15541386 | 0.71 | MEN1 (0.33) | ALOX15 | |
| SCHEMBL19953391 | 0.70 | MAPT (0.36) | MAPTKDM4ESMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149106-B2 | Two-component polyurethane adhesive having substantially temperature-independent mechanical properties and high strength | SIKA TECHNOLOGY AG (CH) | 2021-10-19 | — | — | US | disclosed |
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| EP-3494155-B1 | TWO COMPONENT POLYURETHANE ADHESIVE WITH SUBSTANTIALLY TEMPERATURE INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH | SIKA TECH AG (CH) | 2020-09-09 | — | — | EP | disclosed |
| US-10414875-B2 | Catalyst containing guanidine groups | SIKA TECHNOLOGY AG (CH) | 2019-09-17 | — | — | US | disclosed |
| US-10392480-B2 | Catalyst containing amidine groups | SIKA TECHNOLOGY AG (CH) | 2019-08-27 | — | — | US | disclosed |
| EP-3494155-A1 | TWO-COMPONENT POLYURETHANE ADHESIVE HAVING SUBSTANTIALLY TEMPERATURE-INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH | Sika Technology AG (CH) | 2019-06-12 | — | — | EP | disclosed |
| US-20190169354-A1 | TWO-COMPONENT POLYURETHANE ADHESIVE HAVING SUBSTANTIALLY TEMPERATURE-INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH | SIKA TECHNOLOGY AG (CH) | 2019-06-06 | — | — | US | disclosed |
| WO-2018162587-A1 | WATER-SWELLABLE MOISTURE CURING ONE-COMPONENT POLYURETHANE SEALANT | SIKA TECHNOLOGY AG (CH) | 2018-09-13 | — | — | WO | disclosed |
| EP-3372652-A1 | WATER-SWELLABLE MOISTURE CURING ONE-COMPONENT POLYURETHANE SEALANT | SIKA TECHNOLOGY AG (CH) | 2018-09-12 | — | — | EP | disclosed |
| US-8389772-B2 | Aldehydes containing hydroxl groups | SIKA TECHNOLOGY AG (CH) | 2013-03-05 | — | — | US | disclosed |
| US-20110195242-A1 | ALDEHYDES CONTAINING HYDROXL GROUPS | SIKA TECHNOLOGY AG (CH) | 2011-08-11 | — | — | US | disclosed |
| EP-2200973-B1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-07-13 | — | — | EP | disclosed |
| US-20100190014-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-07-29 | — | — | US | disclosed |
| EP-2200973-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| EP-2200970-A1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009027510-A1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009027511-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| EP-2030965-A1 | Aldehydes containing hydroxyl groups | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| EP-2030967-A1 | Aldimines containing hydroxyl groups and compositions containing aldimine | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195242-A1 | ALDEHYDES CONTAINING HYDROXL GROUPS | ALDH7A1, ALDH1A1, AOX1 | MAPT 1835/4885KDM4E 559/4885SMN1; SMN2 3595/4885 |
| US-20100190014-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | ADH5, ADH1A, ADH1C | MAPT 1624/4885KDM4E 1105/4885SMN1; SMN2 2910/4885 |
| US-10414875-B2 | Catalyst containing guanidine groups | GMPS, GMNN, RNMT | MAPT 1522/4885KDM4E 998/4885SMN1; SMN2 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.