Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704281 | 0.82 | — | — | |
| SCHEMBL11790059 | 0.80 | PDK1 (0.34) | PDK1 | |
| SCHEMBL6440630 | 0.78 | PDK1 (0.34) | PDK1 | |
| SCHEMBL4813774 | 0.78 | DRD2 (0.33) | — | |
| SCHEMBL1897295 | 0.77 | PDK1 (0.33) | PDK1 | |
| SCHEMBL6444394 | 0.76 | — | — | |
| SCHEMBL6441658 | 0.74 | GBA1 (0.31) | PDK1 | |
| SCHEMBL11701827 | 0.73 | TP53 (0.33) | — | |
| SCHEMBL11403957 | 0.73 | — | — | |
| SCHEMBL28110826 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778814-B | There is the aldehyde of hydroxyl | SIKA技术股份公司 | 2016-08-03 | — | — | CN | disclosed |
| EP-2200970-B1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-01-06 | — | — | EP | disclosed |
| CN-101765583-B | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG | 2014-06-04 | — | — | CN | disclosed |
| US-8455100-B2 | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG (CH) | 2013-06-04 | — | — | US | disclosed |
| EP-1537158-B1 | RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS | BASF SE (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-8389772-B2 | Aldehydes containing hydroxl groups | SIKA TECHNOLOGY AG (CH) | 2013-03-05 | — | — | US | disclosed |
| US-20110195242-A1 | ALDEHYDES CONTAINING HYDROXL GROUPS | SIKA TECHNOLOGY AG (CH) | 2011-08-11 | — | — | US | disclosed |
| EP-2200973-B1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-07-13 | — | — | EP | disclosed |
| US-20100190014-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-07-29 | — | — | US | disclosed |
| CN-101778814-A | aldehydes containing hydroxyl groups | SIKA TECHNOLOGY AG | 2010-07-14 | — | — | CN | disclosed |
| EP-2200973-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| EP-2200970-A1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| CN-101765583-A | aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG | 2010-06-30 | — | — | CN | disclosed |
| WO-2009027510-A1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009027511-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| EP-2030965-A1 | Aldehydes containing hydroxyl groups | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| EP-2030967-A1 | Aldimines containing hydroxyl groups and compositions containing aldimine | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| US-20050244652-A1 | Radiation curable polyurethanes with capped amino groups | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-03 | — | — | US | disclosed |
| EP-1537158-A1 | RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022621-A1 | RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195242-A1 | ALDEHYDES CONTAINING HYDROXL GROUPS | ALDH7A1, ALDH1A1, AOX1 | PDK1 845/4885 |
| US-20100190014-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | ADH5, ADH1A, ADH1C | PDK1 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.