SCHEMBL1289085

SCHEMBL1289085

CC1(C)C[Si](c2ccccc2)(c2ccccc2)OC(c2ccccc2)(c2ccccc2)C1(C)C

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ICMT O60725 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
PAX8 Q06710 1/20 0.31
MCL1 Q07820 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6839562 0.85 ICMT (0.31) ICMTALDH1A1LMNAGAAPAX8
SCHEMBL2232615 0.77 OPRM1 (0.35) ALDH1A1LMNAGAAPAX8MCL1
SCHEMBL11144105 0.71
SCHEMBL2048192 0.68 OPRM1 (0.36) ALDH1A1LMNAGAAPAX8MCL1
SCHEMBL28711657 0.67 AKR1C1 (0.30)
SCHEMBL29187184 0.64
SCHEMBL1055776 0.64 TET3 (0.30)
SCHEMBL23748538 0.63 TSHR (0.33) ALDH1A1LMNAGAAPAX8MCL1
SCHEMBL27962277 0.63 DRD4 (0.31)
SCHEMBL3471398 0.62 CHRNB2 (0.41) ALDH1A1LMNAGAAPAX8MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106456520-B Solid lipstick compositions having improved hardness 欧莱雅 2020-02-21 CN disclosed
EP-3157497-B1 SOLID LIPSTICK COMPOSITION HAVING IMPROVED HARDNESS OREAL (FR) 2018-10-31 EP disclosed
US-9789055-B2 Solid lipstick composition having improved hardness L'OREAL (FR) 2017-10-17 US disclosed
US-9708521-B2 Systems and methods employing low molecular weight gelators for crude oil, petroleum product or chemical spill containment and remediation GEORGETOWN UNIVERSITY (US) 2017-07-18 US disclosed
EP-3157497-A1 SOLID LIPSTICK COMPOSITION HAVING IMPROVED HARDNESS L'Oréal (FR) 2017-04-26 EP disclosed
US-20150366779-A1 SOLID LIPSTICK COMPOSITION HAVING IMPROVED HARDNESS L'OREAL (FR) 2015-12-24 US disclosed
US-20150366782-A1 LIPSTICK COMPOSITION HAVING IMPROVED GLOSS AND WEAR L'OREAL (FR) 2015-12-24 US disclosed
WO-2015193415-A1 SOLID LIPSTICK COMPOSITION HAVING IMPROVED HARDNESS L'OREAL (FR) 2015-12-23 WO disclosed
US-9109150-B2 Fast recovery of thixotropy by organogels with low molecular weight gelators GEORGETOWN UNIVERSITY (US) 2015-08-18 US disclosed
EP-2609066-A1 LOW MOLECULAR WEIGHT GELATORS FOR CRUDE OIL, PETROLEUM PRODUCT OR CHEMICAL SPILL CONTAINMENT Georgetown University (US) 2013-07-03 EP disclosed
US-20110251294-A1 FAST RECOVERY OF THIXOTROPY BY ORGANOGELS WITH LOW MOLECULAR WEIGHT GELATORS GEORGETOWN UNIVERSITY (US) 2011-10-13 US disclosed
US-8025869-B2 Cosmetic compositions having enhanced wear properties L'ORÉAL (FR) 2011-09-27 US disclosed
US-20070093619-A1 Compositions having enhanced cosmetic properties L'OREAL (FR) 2007-04-26 US disclosed
US-20060292096-A1 Cosmetic compositions having enhanced wear properties L'OREAL (FR) 2006-12-28 US disclosed
US-5891356-A LIQUID CRYSTAL COMPOUND IN WHICH A PLURALITY OF LIQUID CRYSTAL GROUPS ARE BONDED TO A MOLECULAR CHAIN EITHER DIRECTLY OR VIA A SPACER, OR COMPRISES A LYOTROPIC LIQUID CRYSTAL COMPRISING A SOLUTE AND A SOLVENT. ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-04-06 US disclosed
EP-0657526-B1 Homogeneous electrorheological fluid ASAHI CHEMICAL IND (JP) 1997-08-06 EP disclosed
EP-0478034-B1 Homogeneous electrorhelogical fluid ASAHI CHEMICAL IND (JP) 1995-11-15 EP disclosed
EP-0657526-A2 Homogeneous electrorheological fluid Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1995-06-14 EP disclosed
US-5354489-A Electrorheological fluids ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-10-11 US disclosed
EP-0478034-A1 Homogeneous electrorhelogical fluid Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060292096-A1 Cosmetic compositions having enhanced wear properties RARA, RARG, CUTA ICMT 3991/4885ALDH1A1 1114/4885LMNA 815/4885
US-20110251294-A1 FAST RECOVERY OF THIXOTROPY BY ORGANOGELS WITH LOW MOLECULAR WEIGHT GELATORS TBXAS1, TBXA2R, TSNAX ICMT 1891/4885ALDH1A1 1454/4885LMNA 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.