Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15311992 | 0.87 | PDE5A (0.37) | PDE5AGAAL3MBTL1KMT2AMEP1B | |
| SCHEMBL143706 | 0.87 | PDE5A (0.37) | PDE5AGAAL3MBTL1KMT2AMEP1B | |
| Ethylene Glycol SCHEMBL7087133 | 0.85 | ALDH1A1 (0.35) | GAAL3MBTL1KMT2AMEP1BALDH1A1 | |
| SCHEMBL8470868 | 0.84 | PDE5A (0.44) | PDE5AGAAL3MBTL1KMT2AMEP1B | |
| SCHEMBL26637678 | 0.83 | PDE5A (0.49) | PDE5AMEP1BPOLBMAPTRAPGEF4 | |
| Water SCHEMBL11279317 | 0.81 | ALDH1A1 (0.36) | GAAL3MBTL1KMT2AMEP1BALDH1A1 | |
| SCHEMBL8464278 | 0.81 | LMNA (0.37) | GAAL3MBTL1KMT2AMEP1BALDH1A1 | |
| SCHEMBL531432 | 0.79 | LMNA (0.47) | GAAL3MBTL1KMT2AALDH1A1RECQL | |
| SCHEMBL9101570 | 0.79 | LMNA (0.38) | GAAL3MBTL1KMT2AMEP1BALDH1A1 | |
| SCHEMBL30716899 | 0.79 | LMNA (0.38) | GAAL3MBTL1KMT2AMEP1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738023-B2 | Method for producing 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione-related substance, and said related substance | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738023-B2 | Method for producing 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione-related substance, and said related substance | ADH1C, ADH5, ADH1A | PDE5A 2741/4885GAA 2950/4885L3MBTL1 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.