SCHEMBL22485368

SCHEMBL22485368

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CCCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(O)CO

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 6/20 0.50
▸ C5AR1 P21730 1/20 0.49
▸ KISS1R Q969F8 6/20 0.48
▸ NPBWR1 P48145 1/20 0.47
▸ PRKACB P22694 1/20 0.47
▸ CCKBR P32239 1/20 0.47
▸ IL23R Q5VWK5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22339063 0.93 MC4R (0.53) MC4RC5AR1KISS1RNPBWR1PRKACB
SCHEMBL14811912 0.92 MC4R (0.57) MC4RKISS1RNPBWR1CCKBR
SCHEMBL22485392 0.90 MC4R (0.54) MC4RC5AR1KISS1RNPBWR1PRKACB
SCHEMBL22485206 0.87 MC4R (0.50) MC4RC5AR1KISS1RNPBWR1PRKACB
SCHEMBL22339064 0.87 MC4R (0.55) MC4RKISS1RNPBWR1CCKBR
SCHEMBL5501891 0.86 KISS1R (0.55) MC4RKISS1RNPBWR1IL23R
SCHEMBL14117706 0.86 MC4R (0.55) MC4RKISS1RNPBWR1CCKBRIL23R
SCHEMBL15691474 0.84 NPBWR1 (0.52) MC4RC5AR1KISS1RNPBWR1PRKACB
SCHEMBL22339062 0.83 NPY4R (0.55) MC4RKISS1R
SCHEMBL29511100 0.83 C5AR1 (0.51) MC4RC5AR1KISS1RNPBWR1PRKACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS B.V. (NL) 2020-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES VIP, CLPP, SGTA MC4R 1528/4885C5AR1 521/4885KISS1R 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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