SCHEMBL223392

SCHEMBL223392

CCCC(CC)OC(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.46
PRKCD Q05655 2/20 0.46
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
LMNA P02545 3/20 0.38
TSHR P16473 3/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.37
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CTSK P43235 2/20 0.36
AKR1A1 P14550 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17805629 0.91 CTSK (0.42) PRKCAPRKCDCA1CA2LMNA
SCHEMBL11257974 0.87 CA2 (0.50) PRKCAPRKCDCA1CA2TSHR
SCHEMBL15360245 0.87 CA2 (0.50) PRKCAPRKCDCA1CA2TSHR
SCHEMBL224781 0.85
SCHEMBL3647097 0.85 PRKCA (0.44) PRKCAPRKCDCA1CA2MAPT
SCHEMBL11757686 0.84 PRKCA (0.38) PRKCAPRKCDCA1CA2LMNA
SCHEMBL1437005 0.84 MAPT (0.41) PRKCAPRKCDCA1CA2LMNA
SCHEMBL11292577 0.84 PRKCA (0.43) PRKCAPRKCDCA1CA2LMNA
SCHEMBL30746068 0.84 PRKCA (0.43) PRKCAPRKCDCA1CA2LMNA
Hydrochloric Acid SCHEMBL28169807 0.84 PRKCA (0.43) PRKCAPRKCDCA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024094637-A1 PROCESS FOR THE PREPARATION OF CYCLIC KETONES ARXADA AG (CH) 2024-05-10 WO disclosed
EP-2308838-B1 NITROGEN-CONTAINING AROMATIC HETEROCYCLYL COMPOUND DAIICHI SANKYO CO LTD (JP) 2016-02-17 EP disclosed
US-9150563-B2 Nitrogen-containing aromatic heterocyclyl compound DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-10-06 US disclosed
US-9045423-B2 Prophylactic and/or therapeutic agent for anemia comprising tetrahydroquinoline compound as active ingredient KOWA COMPANY, LTD. (JP) 2015-06-02 US disclosed
US-20140249144-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT KOWA COMPANY, LTD. (JP) 2014-09-04 US disclosed
US-8791090-B2 Prophylactic and/or therapeutic agent for anemia comprising tetrahydroquinoline compound as active ingredient KOWA COMPANY, LTD. (JP) 2014-07-29 US disclosed
US-20140187592-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLYL COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-07-03 US disclosed
US-8648103-B2 Nitrogen-containing aromatic heterocyclyl compound DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-02-11 US disclosed
CN-102077282-B Image recording media and imaging layers HEWLETT PACKARD DEVELOPMENT CO 2013-08-28 CN disclosed
US-20130172345-A1 1-ACYL-4-(PHENOXY, BENZYLOXY, OR PHENYLAMINO)-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES KOWA COMPANY, LTD. (JP) 2013-07-04 US disclosed
US-6809114-B2 ANTIARRHYTHMIC AGENTS; SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-7-NITRO-4-N-PENTYLAMINO-2H-1 -BENZOPYRAN-3-OL NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-10-26 US disclosed
EP-1360182-B1 4-AMINOBENZOPYRAN DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2004-08-11 EP disclosed
US-20040068002-A1 4-aminobenzopyran derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-08 US disclosed
EP-1360182-A1 4-AMINOBENZOPYRAN DERIVATIVES Nissan Chemical Industries, Ltd. (JP) 2003-11-12 EP disclosed
EP-0934938-B1 SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME ZERIA PHARM CO LTD (JP) 2003-01-15 EP disclosed
WO-2002064581-A1 4-AMINOBENZOPYRAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-22 WO disclosed
US-6121301-A ADMINISTERING TO PREVENT OR TREAT GASTROINTESTINAL DYSMOTILITY; COMPOUNDS SUCH AS 2-((N-(3-CYANOBENZOYL)AMINO)-4-((3-DIISOPROPYLAMINOPROPYL)AMINOCARBONYL)-1,3-THIAZOLE ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-09-19 US disclosed
EP-0934938-A1 SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-08-11 EP disclosed
US-4381403-A Process for the preparation of N-monosubstituted carbamic acid esters ATLANTIC RICHFIELD COMPANY (US) 1983-04-26 US disclosed
US-4336402-A Process for the preparation of N-alkyl-monosubstituted carbamic acid esters ATLANTIC RICHFIELD COMPANY (US) 1982-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249144-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT EPOR, HBG1, HBG2 PRKCA 3942/4885PRKCD 3975/4885CA1 2873/4885
US-20040068002-A1 4-aminobenzopyran derivatives CYP2D6, KCNH1, CYP2B6 PRKCA 3648/4885PRKCD 1691/4885CA1 1207/4885
US-20140187592-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLYL COMPOUND NPR1, NPR3, NPC1 PRKCA 2647/4885PRKCD 2184/4885CA1 4667/4885
US-20130172345-A1 1-ACYL-4-(PHENOXY, BENZYLOXY, OR PHENYLAMINO)-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES EPOR, HBG2, HBG1 PRKCA 4337/4885PRKCD 4441/4885CA1 3830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.