Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241082 | 0.80 | SLC6A2 (0.71) | SMN1; SMN2SLC6A2SLC6A4PRMT6TSHR | |
| SCHEMBL19135757 | 0.77 | SLC6A2 (0.53) | SMN1; SMN2SLC6A2SLC6A4PRMT6TSHR | |
| SCHEMBL327856 | 0.74 | CCR3 (0.66) | PRMT6CCR3CARM1PRMT3PRMT1 | |
| SCHEMBL22324836 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2SLC6A2SLC6A4PRMT6TSHR | |
| SCHEMBL3540368 | 0.73 | SLC6A2 (0.63) | SMN1; SMN2SLC6A2SLC6A4PRMT6TSHR | |
| SCHEMBL3436965 | 0.73 | PRMT6 (0.62) | SLC6A2SLC6A4PRMT6CCR3CARM1 | |
| SCHEMBL941899 | 0.73 | SLC6A2 (0.79) | SMN1; SMN2SLC6A2SLC6A4PRMT6TSHR | |
| SCHEMBL6427944 | 0.73 | MEN1 (0.61) | SMN1; SMN2SLC6A2SLC6A4PRMT6TSHR | |
| SCHEMBL7850831 | 0.72 | HRH3 (0.57) | SLC6A2SLC6A4PRMT6TSHRCCR3 | |
| SCHEMBL2952169 | 0.72 | MEN1 (0.65) | SLC6A2SLC6A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144797-A1 | 20-HETE FORMATION INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-05-12 | — | — | US | disclosed |
| WO-2020163689-A1 | 20-HETE FORMATION INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144797-A1 | 20-HETE FORMATION INHIBITORS | CYP4A22, ALOX5, ALOX15 | SMN1; SMN2 2585/4885SLC6A2 1927/4885SLC6A4 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.